Unipi Team Leader: Prof. Andrea Guzzetta, Dipartimento di Medicina Clinica e Sperimentale
Despite advances in the medical management of high-risk pregnancies and deliveries, cerebral palsy (CP) remains the most common physical disability in childhood in high and low-to-middle income (LMIC). In addition, caregivers of children with CP are at higher risk of psychiatric issues, further increasing health and socio-economic burden to the families. In spite of the scientific advancements in early detection and intervention (EI) in CP, there is a lack of implementation into clinical service delivery.
The overarching aim of the BORNTOGETTHERE program is to exploit current evidence on early detection and efficacy of EI for infants at high risk of CP by implementing the International Clinical Practice Guideline in Europe (Italy, Denmark, Netherlands), LMIC (Georgia, Sri Lanka) and hard to reach populations (Remote Queensland and Western Australia).
It will provide a multifaceted knowledge translation approach focused on i) optimizing context-specific health programs for early detection of CP, thus reducing age at diagnosis and age at referral to EI; ii) optimizing early functional characterization of infants with CP, thereby fostering personalized EI and preventing secondary complications (i.e. hip dislocation) and iii) testing the implementation of integrated EI programs adapted to country-specific welfare systems.
The protocol of service delivery will result from the adaptation of early detection and EI programs based on the proven, effective intervention strategies, and those that are included into ongoing research based on effectiveness shown with preliminary data. This framework will be validated in real life varying world conditions through a large implementation program and a multicentre parallel controlled trial. The main beneficiaries will include a wide range of stakeholders: not only concerned families and communities but also policy makers, public authorities, the media, and citizen groups to ensure the translation of evidence into routine practice.
Coordinator
Università di Pisa
Participants
- Fondazione Stella Maris, Italy
- KOBENHAVNS UNIVERSITET, Denmark
- ACADEMISCH ZIEKENHUIS GRONINGEN, Netherlands
- CEREBRAL PALSY LANKA FOUNDATION, Sri Lanka
- HUBSTRACT SRL, Italy
- THE UNIVERSITY OF QUEENSLAND, Australia
- DAVID TVILDIANI MEDICAL UNIVERSITY LLC, Georgia
- FONDAZIONE TOSCANA LIFE SCIENCES, Italy
Start date 1 Gennaio 2020
End date 31 Dicembre 2023
Project cost € € 4 010 000
Project funding € € 3 700 000
Unipi quota € 852 075
Call title H2020-SC1-2019-Two-Stage-RTD
Unipi role Coordinator
Website: http://borntogetthere.eu/